Aromasin

Exemestane — Aromasin by Dragon Pharma

Aromasin is Dragon Pharma's formulation of Exemestane at 25mg per tablet — a steroidal aromatase inhibitor that binds the aromatase enzyme irreversibly. Supplied in a 100-tablet pack, Aromasin offers an alternative mechanism to non-steroidal AIs like Arimidex for managing estrogen-related side effects during a cycle or PCT.

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What Is Exemestane (Aromasin)?

Exemestane is a steroidal aromatase inhibitor — structurally similar to androgens, it binds permanently to the aromatase enzyme, irreversibly inactivating it ("suicide inhibition"). This differs from non-steroidal AIs like Anastrozole, which bind reversibly and are displaced as drug levels fall. Because Exemestane permanently inactivates each enzyme molecule it binds, the body must synthesise new aromatase enzyme to restore activity, which some users find produces a different practical dosing pattern compared to reversible AIs.

Effects and Benefits

• Reduces circulating estrogen levels through irreversible aromatase inhibition
• Manages water retention and bloating from elevated estrogen on aromatising compounds
• Reduces gynecomastia risk during cycles with testosterone or other aromatising AAS
• Some users report a more favourable impact on lipid profile (cholesterol) compared to non-steroidal AIs, though individual response varies
• Its steroidal structure means it may have mild direct effects on the androgen receptor in addition to its aromatase inhibition, distinguishing it from purely non-steroidal AIs

Dosage and Administration

Aromasin's 25mg tablet is commonly split in half for the lower doses many users find sufficient on-cycle. With a half-life of approximately 24 hours, daily or every-other-day dosing is typical. As with any AI, the correct dose depends on the aromatising load of the compounds being used — many users start conservatively and adjust based on symptoms or bloodwork (estradiol levels).